Forty five. Schmit TL, Ledesma MC, Ahmad N. Modulating polo-like kinase one like a

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MCM proteins as diagnostic and prognostic tumor markers while in the medical location. Histol Histopathol 2010; 25: 351?70. 58. Patel D, Incassati A, Wang N, McCance DJ. Human papillomavirus form 16 E6 and E7 result in PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/24247322 polyploidy in human keratinocytes and Es Of course Of course Of course Of course Of course No Indeed Sure Indeed Yes up-regulation of G2-M-phase proteins. Most cancers res 2004; 64: 1299?306. 59. Fukasawa K. Centrosome amplification, chromosome instability and most cancers enhancement. Cancer Lett 2005; 230: six?9. 60. Kramer A, Neben K, Ho Advertisement. Centrosome aberrations in hematological malignancies. Nature testimonials. Mol Cell Biol 2005; 6: 476?86. 49. Ferguson RL, Maller JL. Cyclin E-dependent localization of MCM5 regulates centrosome duplication. J Cell Sci 2008; 121(Part 19): 3224?232. 50. Ferguson RL, Pascreau G, Maller JL. The cyclin A centrosomal localization sequence recruits MCM5 and Orc1 to control centrosome reduplication. J Mobile Sci 2010; 123(Component 16): 2743?749. fifty one. Hemerly AS, Prasanth SG, Siddiqui K, Stillman B. Orc1 controls centriole and centrosome copy variety in human cells. Science 2009; 323: 789?93. PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/21034305 fifty two. Saha T, Ghosh S, Vassilev A, DePamphilis ML. Ubiquitylation phosphorylation and Orc2 modulate the subcellular location of Orc1 and stop it from inducing apoptosis. J Cell Sci 2006; 119(Component 7): 1371?382. fifty three. Meyer R, Fofanov V, Panigrahi A, Merchant F, Zhang N, Pati D. Overexpression and mislocalization on the chromosomal segregation protein separase in numerous human cancers. Clin Most cancers Res 2009; fifteen: 2703?710. fifty four. Strebhardt K. Multifaceted polo-like kinases: drug targets and antitargets for most cancers therapy. Character Testimonials. Drug Discov 2010; nine: 643?sixty. 55. Di Paola D, Zannis-Hadjopoulos M. Comparative analysis of pre-replication advanced proteins in reworked and typical cells. J Cell Biochem 2012; 113: 1333?347. fifty six. Semple JW, Duncker BP. ORC-associated replication things as biomarkers for most cancers. Biotechnol Adv 2004; 22: 621?31. 57. Giaginis C, Vgenopoulou S, Vielh P, Theocharis S. MCM proteins as diagnostic and prognostic tumor markers within the clinical environment. Histol Histopathol 2010; 25: 351?70. 58. Patel D, Incassati A, Wang N, McCance DJ. Human papillomavirus kind 16 E6 and E7 bring about PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/24247322 polyploidy in human keratinocytes and up-regulation of G2-M-phase proteins. Cancer res 2004; 64: 1299?306. 59. Fukasawa K. Centrosome amplification, chromosome instability and cancer advancement. Cancer Lett 2005; 230: six?9. sixty. Kramer A, Neben K, Ho Advert. Centrosome aberrations in hematological malignancies. Cell Biol Int 2005; 29: 375?83. sixty one. Leber B, Maier B, Fuchs F, Chi J, Riffel P, Anderhub S et al. Proteins necessary for centrosome clustering in cancer cells. Sci Transl Med 2010; two: 33ra38. sixty two. Kramer A, Maier B, Bartek J. Centrosome clustering and chromosomal (in)balance: a make a difference of life and death. Molecular Oncolo 2011; five: 324?35. sixty three. Ganem NJ, Godinho SA, Pellman D. A mechanism linking further centrosomes to chromosomal instability. Mother nature 2009; 460: 278?eighty two. 64. Silkworth WT, Nardi IK, Scholl LM, Cimini D.